干细胞/抗小鼠NK1.1（CD161）抗体，克隆PK136/25 u00b5g/60103PB
商品编号：
60103PB
品牌：
StemCells Inc
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview
The PK136 antibody reacts with murine NK1.1 (CD161), an ~80 kDa homodimeric type 2 transmembrane glycoprotein and C-type lectin receptor expressed on NK cells, NK-T cells, and rare subsets of T cells and monocytes in select strains of mice. NK1.1 is encoded by the Klrb1b and Klrb1c genes, which specify CD161b and CD161c polypeptides, respectively. CD161b is expressed only by Swiss NIH and SJL mice, and CD161c by certain strains such as C57BL, FVB/N, and NZB (but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, NOD, SJL, or 129). NK1.1 has functional roles in modulating several processes, including the activation and proliferation of NK cells, induction of interferon-γ production, and release of cytotoxic granules. Its expression on the cell surface is specifically upregulated by IL-12. For detection of NK cells in NK1.1- strains, Anti-Mouse CD49b Antibody, Clone DX5 (Catalog #60020) is recommended. DX5 recognizes CD49b (integrin α2), another commonly used NK cell marker.
Subtype:
Primary Antibodies
Target Antigen:
NK1.1 (CD161)
Alternative Names:
CD161b, CD161c, Klrb1b, Klrb1c, Ly-55, Ly-59, NK-1.1, NKRP1, NKRP1a, NKRP1b
Reactive Species:
Mouse
Conjugation:
Biotin; FITC; PE; Unconjugated
Host Species:
Mouse
Cell Type:
NK Cells
Application:
Cell Isolation; CyTOF; Depletion; Flow Cytometry; Functional Assay; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation
Area of Interest:
Immunology
Clone:
PK136
Gene ID:
17059
Isotype:
IgG2a, kappa
品牌介绍
STEMCELL Technologies 成立于 1993 年，是加拿大最大的生物科技公司，为生命科学研究领域提供专业的细胞培养基和细胞分选产品。 我们的使命是为科学的不断进步提供高品质、创新的试剂、工具和服务，本着 Scientists Helping Scientists 的精神，用我们的服务帮助您的科学研究。 STEMCELL Technologies 为全球 70 多个国家提供超过 3000 种分子生物学工具，以支持干细胞、免疫学、癌症、类器官、基因编辑、细胞治疗和再生医学等领域的科学研究。我们的 mTeSR1™、MethoCult™ 和 EasySep™ 已经成为多能干细胞培养、造血干细胞鉴定以及无柱细胞分选的金标准；许多工具为广大的科研实验室所熟知。 此外，我们研发了一系列针对不同类器官的培养基，包括肠道类器官、脑类器官、肝类器官、胰类器官、上呼吸道类器官等，身体力行地推动类器官研究领域的发展。 STEMCELL Technologies，源于科研，归于科研。与您在科学的道路上携手前行！* 欲了解您区域的代理商信息，请通过电话 400-885-9050 或者邮箱 info.cn@stemcell.com 与我们联系。
