干细胞/SARS-CoV-2重组棘突蛋白,aa16-685(HEK293表达)/1000 u00b5g/100-0595
商品编号:
100-0595
品牌:
StemCells Inc
市场价:
¥0.00
美元价:
0.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview
SARS-CoV-2 Recombinant Spike Protein, aa16-685 is expressed in HEK293 cells and is one of four structural proteins encoded by the SARS-CoV-2 genome. The Spike Protein plays a key role in attachment to host cells, allowing invasion through clathrin-mediated endocytosis. The Spike Protein can be cleaved by host cell proteases after aa685 to yield the N-terminal S1 subunit and C-terminal S2 region. The S1 subunit is responsible for interacting with the host cell receptor (angiotensin-converting enzyme II) through a receptor-binding domain that is highly conserved with SARS-CoV. The S1 subunit has two conformations: a ‘down’ conformation in which the receptor is inaccessible, and an ‘up’ conformation in which the receptor is accessible. These conformational changes are key for monoclonal antibody drugs and vaccine development. SARS-CoV-2 Recombinant Spike Protein contains a polyhistidine tag at the amino terminus; it also contains a FLAG tag at the carboxy terminus.
Alternative Names:
S protein; Spike glycoprotein
Area of Interest:
Infectious Diseases
Molecular Weight:
79.5 kDa
Purity:
≥ 85%
品牌介绍
STEMCELL Technologies 成立于 1993 年,是加拿大最大的生物科技公司,为生命科学研究领域提供专业的细胞培养基和细胞分选产品。 我们的使命是为科学的不断进步提供高品质、创新的试剂、工具和服务,本着 Scientists Helping Scientists 的精神,用我们的服务帮助您的科学研究。 STEMCELL Technologies 为全球 70 多个国家提供超过 3000 种分子生物学工具,以支持干细胞、免疫学、癌症、类器官、基因编辑、细胞治疗和再生医学等领域的科学研究。我们的 mTeSR1™、MethoCult™ 和 EasySep™ 已经成为多能干细胞培养、造血干细胞鉴定以及无柱细胞分选的金标准;许多工具为广大的科研实验室所熟知。 此外,我们研发了一系列针对不同类器官的培养基,包括肠道类器官、脑类器官、肝类器官、胰类器官、上呼吸道类器官等,身体力行地推动类器官研究领域的发展。 STEMCELL Technologies,源于科研,归于科研。与您在科学的道路上携手前行!* 欲了解您区域的代理商信息,请通过电话 400-885-9050 或者邮箱 info.cn@stemcell.com 与我们联系。